401077 Introduction to Biostatistics, Autumn 2016 Assignment 3 (Due SundayOctober 23, 2016) Please answer each question in the template document provided and submit via Turnitin by the due date. A total of 40 marks are available and this assignment is worth 40% of your overall grade. Question 1 (18 marks) Read the paper Beavers KM, Beavers DP, Houston DK, at al. Associations between body composition and gait-speed decline: results from the Health, Aging and Body Composition study. American Journal of Clinical Nutrition 20133.97:552-560. Critically appraise of the statistical material in this paper against items 10, 12-17 of the STROBE checklist. Present your review as a 400-500 word (approx.) report. Notes: - Only review the provided paper Elias et al, 1993 do not read any other papers. A reference list is not required. - Restrict your review to how well Elias et al have documented their statistical methods – that is, items 10, 12-17 of STROBE only. - You may not have to address every item, just describe the major strengths and weaknesses of Elias et al's descriptions of their statistical methods. Question 2 (22 marks)Note: Students will get different answers as the data sets differ. Using the data set assigned to you in Assignment 2 address the following research question: Does walking speed predict total cholesterol after correcting for overweight in the population of Australian recent retirees? Notes: - You should only use the variables 'TCholest', 'WSpeed' and 'overweight'. - Correcting for 'overweight' is just including 'overweight' in the regression model. When overweight is in the model all other variables are corrected for it. - Do report the results of your descriptive analyses o Well labelled graphs can be copied from R Commander o Summary statistics and tables should be manually typed with appropriate labels o Summarise the main findings of your descriptive analyses in one or two paragraphs - Do report the results of your statistical inference o Descriptions and results of relevant hypothesis tests, confidence intervals and/or regression models should be manually typed. o Summarise the main findings of your statistical inference in one or two paragraphs. - Do remember to answer the research question o Write a final paragraph which summarises the key findings and you answer to the research question. - Do check the Learning Guide for the marking criteria - Do write your answers yourself and keep them private.