Answering Questions on Immunity

Q Which of the following is FALSE regarding autoimmunity?

It involves a breakdown of "tolerance"

The body begins to recognize foreign antigens as "self" There can be a genetic predisposition to develop the disorders

Development of autoimmune disorders can be related to exposure to antigens such as drugs or infections

The type of hypersensitivity where antigen-antibody complexes form and are deposited in tissues is:

IgE - mediated hypersensitivity Type I hypersensitivity

Type III hypersensitivity

Isoimmunity All of the following are types of hypersensitivity EXCEPT: HIV disease

Systemic lupus erythematosus

Rheumatoid arthritis

Allergy Clinical manifestations related to the release of histamine include all of the following EXCEPT:

Vomiting/diarrhea

Itching/erythema Bronchial dilation

Increased vascular permeability

Which of the following is FALSE regarding Systemic Lupus Erythematosus (SLE)? It consists of a Type III hypersensitivity reaction There is increased frequency in females

The main problem is over-reaction of T cells

It is an autoimmune disease Which of the following is FALSE regarding Rheumatoid Arthritis? It consists of a Type III hypersensitivity reaction

It consists of a Type IV hypersensitivity reaction

White Blood Cells enter the synovial space causing further inflammation and destruction

It is progressively chronic, with usually no remissions Which of the following is a FALSE statement? Primary immune deficiency can be due to a genetic cause

Burns can be a cause of secondary immune deficiency

Both primary and secondary immune deficiencies result from cancer or viral infection

Secondary immune deficiency may result from normal physiologic changes Which of the following best describes HIV infection? It is a bacterial disease in which the individual becomes extremely susceptible to life-threatening infections

The HIV particles engulf T helper cells The virus can spread through airborne mechanisms

The HIV particles insert their own DNA into the T cell DNA A clinical manifestation that is similar to anaphylaxis, systemic lupus erythematosus, and rheumatoid arthritis is: Bronchial constriction General systemic manifestations of inflammation (e.g. fever, fatigue, weakness, achiness) Arthritis of joints

Renal disease Which disorder is characterized by an over-production of IgG which causes antigen-antibody complexes to be formed and deposited in vessel walls?

Systemic Lupus Erythematosus Rheumatoid Arthritis

HIV Disease

Anaphylaxis